Sunday, April 7, 2013

EU minimum tax legislation for cigarettes has had no effect on smoking prevalence, according to new Spanish study

Apr. 5, 2013 ? Up to 2009 there is no statistically significant evidence of any reduction in smoking amongst men -- and very little evidence of a reduction in smoking amongst women -- resulting from the introduction of EU minimum tax legislation in Spain in 2006. This is despite the price of cigarettes rising up to three times faster than before the legislation came into effect, according to a new study published online in the journal Nicotine and Tobacco Research.

The World Health Organization's Framework Convention on Tobacco Control exhorts Parties to implement tax policies aimed at reducing tobacco consumption. As a signatory, the European Union passed legislation [i] requiring Member States to apply cigarette taxes to ensure that, as of January 1st 2014, at least 90 ? per 1000 units are excised, regardless of brand or category. Many Member States anticipated this move, and introduced taxation legislation.

Spain's minimum tax on manufactured cigarettes legislation has been operating since February 2006. However, the Spanish territory of the Canary Islands is subject to a special tax measures aimed at stimulating their distant offshore economy, and therefore tobacco products in the Canary Islands were not subject to the type of excise duties that were implemented elsewhere in Spain (mainland and the Balearics). This study was therefore able to compare cigarette prices and smoking prevalence in both areas.

?ngel L?pez-Nicol?s, Lourdes Badillo-Amador, and M. Bel?n Cobacho-Tornel found that prior to the legislation coming into effect in 2006, the annual increase of cigarette prices in both the Canary Islands and the rest of Spain were quite similar, at an average of 5%. However, after 2006, the difference is stark: prices rose by 44% before taking inflation (8.3%) into account in Spain in the years 2006-2010, but by only 10% before inflation (8.5%) in the Canary Islands during the same period.

The authors then examined both immediate and longer-term effects on smoking prevalence after the introduction of the legislation and found that the hikes in cigarette prices do not seem to have affected smoking prevalence amongst males, either shortly after the reform or three years hence. In the case of women, the study found no significant effects in the short term, with estimates ranging between 3.36% and 4.3% in the long term.

Lead author ?ngel L?pez-Nicol?s, of the Universidad Polit?cnica de Cartagena, comments, "the lack of a robust effect on prevalence more than three years hence is surprising given the clear effect on cigarette prices. Indeed, finding a statistically significant effect on prevalence only for females and, even then, with only one of our estimation methods, runs against the well-established notion that smoking prevalence responds to price rises."

The authors looked into the Spanish tobacco market to find out why this might be so. They found that the price of fine cut tobacco for use in hand-rolled cigarettes fell in real terms between 2005 and 2008 and has remained well below that of manufactured cigarettes, with the share of fine cut tobacco over total tobacco sales more than trebling (from 1.6% to 5.1% of sales). This suggests that smokers may have taken up hand-rolled cigarettes since the introduction of the minimum tax legislation, which until 2009 only applied to manufactured cigarettes.

"In this sense," says L?pez-Nicol?s, "the new tax regime has performed poorly in regard of the public health objective of reducing tobacco consumption. It seems that a necessary condition to achieve such a reduction would be to plug the tax loophole that allows fine cut tobacco into the market at a substantive discount compared to manufactured cigarettes.

"As for the EU-wide implications, there is a relevant policy message implied by our results. The countries that have introduced a minimum tax on manufactured cigarettes might achieve little in terms of reductions in smoking prevalence if they allow a tax gap between fine cut tobacco and manufactured cigarettes. Member States should be proactive in this regard if they wish to successfully implement the WHO Framework Convention guidelines on taxation."

[i] Council Directive CD 2011/64/EU

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The above story is reprinted from materials provided by Oxford University Press (OUP), via AlphaGalileo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. A. Lopez-Nicolas, L. Badillo-Amador, M. B. Cobacho-Tornel. Will the European Union's New Tobacco Tax Legislation Lead to Reductions in Smoking Prevalence? Evidence From a Quasi-experiment in Spain. Nicotine & Tobacco Research, 2013; DOI: 10.1093/ntr/ntt038

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/rM6gMkGnKKs/130405064408.htm

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Saturday, April 6, 2013

First magic mushroom depression trial hits stumbling block

By Kate Kelland

LONDON (Reuters) - The world's first clinical trial designed to explore using a hallucinogen from magic mushrooms to treat people with depression has stalled because of British and European rules on the use of illegal drugs in research.

David Nutt, president of the British Neuroscience Association and professor of neuropsychopharmacology at Imperial College London, said he had been granted an ethical green light and funding for the trial, but regulations were blocking it.

"We live in a world of insanity in terms of regulating drugs," he told a neuroscience conference in London on Sunday.

He has previously conducted small experiments on healthy volunteers and found that psilocybin, the psychedelic ingredient in magic mushrooms, has the potential to alleviate severe forms of depression in people who don't respond to other treatments.

Following these promising early results he was awarded a 550,000 pounds ($844,000) grant from the UK's Medical Research Council to conduct a full clinical trial in patients.

But psilocybin is illegal in Britain, and under the United Nations 1971 Convention on Psychotropic Substances it is classified as a Schedule 1 drug - one that has a high potential for abuse and no recognized medical use.

This, Nutt explained, means scientists need a special license to use magic mushrooms for trials in Britain, and the manufacture of a synthetic form of psilocybin for use in patients is tightly controlled by European Union regulations.

Together, this has meant he has so far been unable to find a company able to make and supply the drug for his trial, he said.

"Finding companies who could manufacture the drug and who are prepared to go through the regulatory hoops to get the license, which can take up to a year and triple the price, is proving very difficult," he said.

Nutt said regulatory authorities have a "primitive, old-fashioned attitude that Schedule 1 drugs could never have therapeutic potential", despite the fact that his research and the work done by other teams suggests such drugs may help treat some patients with psychiatric disorders.

Psilocybin - or "magic" - mushrooms grow naturally around the world and have been widely used since ancient times for religious rites and also for recreation.

Researchers in the United States have seen positive results in trials using MDMA, a pure form of the party drug ecstasy, in treating post-traumatic stress disorder.

"What we are trying to do is to tap into the reservoir of under-researched illegal drugs to see if we can find new and beneficial uses for them in people whose lives are often severely affected by illnesses such as depression," Nutt said.

The proposed trial would involve 60 patients with depression who have failed two previous treatments.

During two or three controlled sessions with a therapist, half would be given a synthetic form of psilocybin, and the other 30 a placebo. They would have guided talking therapy to explore negative thinking and issues troubling them, and doctors would follow them up for at least a year.

Nutt secured ethical approval for the trial in March.

In previous research, Nutt found that when healthy volunteers were injected with psilocybin, the drug switched off a part of the brain called the anterior cingulate cortex, which is known to be overactive in people with depression.

"Even in normal people, the more that part of the brain was switched off under the influence of the drug, the better they felt two weeks later. So there was a relationship between that transient switching off of the brain circuit and their subsequent mood,", he said. "This is the basis on which we want to run the trial."

(Reporting by Kate Kelland, editing by Richard Meares)

Source: http://news.yahoo.com/first-magic-mushroom-depression-trial-hits-stumbling-block-231805511.html

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Suspects in Africa drug trade held in NY for trial

NEW YORK ?

A former navy chief of the small West African nation of Guinea-Bissau who is suspected of being a kingpin in the international cocaine trade was brought to the U.S. for trial on drug charges following his arrest at sea by federal drug agents, authorities said Friday.

Four other men apprehended in the operation also were brought to New York for trial, the Drug Enforcement Administration and federal prosecutors said in a joint release. Two more men were arrested in Colombia Friday as part of a related investigation and were awaiting extradition.

Rear Adm. Jose Americo Bubo Na Tchuto and two other Guinea-Bissau nationals were taken into custody Tuesday aboard a vessel in international waters in the eastern Atlantic Ocean while two others were arrested Thursday in a West African country and later transferred to U.S. custody, the release said. Na Tchuto was charged with conspiring to import narcotics into the United States. Three others were charged with conspiring to sell weapons, including surface-to-air missiles, to be used to protect the Revolutionary Armed Forces of Colombia, or FARC, cocaine processing operations in Colombia against U.S. military forces.

The arrests were made based on evidence gathered by confidential sources who posed as representatives or associates of the FARC as they communicated with the defendants beginning last summer, authorities said. Prosecutors said the evidence includes a series of audio recordings and videotaped meetings over several months in Guinea-Bissau.

According to court papers, the defendants agreed to receive cocaine off the coast of Guinea-Bissau and to store the cocaine in storage houses there prior to their shipment to the United States. The U.S. government alleged that the defendants also agreed that a portion of the cocaine would be used to pay Guinea-Bissau government officials to provide safe passage for the cocaine through Guineau-Bissau.

Prosecutors said Na Tchuto discussed shipping ton-quantities of cocaine from South America to Guinea Bissau by sea, saying it was a good time to transport drugs because Guinea Bissau government was weak because of a recent coup d'etat. They said he also said his fee would be $1 million per 1,000 kilograms of cocaine received in Guinea Bissau for the use of a company he owned to hide the shipments before they were moved to the United States. If convicted, he could face life in prison.

DEA Administrator Michele Leonhart called the arrests "significant victories against terrorism and international drug trafficking."

She added: "Alleged narco-terrorists such as these, who traffick drugs in West Africa and elsewhere, are some of the world's most violent and brutal criminals. They have no respect for borders, and no regard for either the rule of law or who they harm as a result of their criminal endeavors. These cases further illustrate frightening links between global drug trafficking and the financing of terror networks."

All five defendants were ordered held without bail after brief appearances in U.S. District Court in Manhattan, where they seemed to struggle to understand Portuguese and creole translators.

Sabrina Shroff, an assistant federal defender, declined to comment after representing Na Tchuto.

The U.S. Treasury Department designated Na Tchuto as a drug kingpin in 2010 for his alleged role in the cocaine trade in Guinea-Bissau, freezing any assets he may have had in the United States. For at least a decade, Guinea-Bissau has played a key role in the drug trade. The country's archipelago of virgin islands has been used by Latin American cartels as a stopover point for ferrying cocaine to Europe, where prices have skyrocketed at the same time that demand for cocaine leveled off in North America.

A former navy chief of staff, Na Tchuto is believed to have played a role in the arrival of a plane carrying hundreds of pounds of cocaine from Venezuela to Guinea-Bissau in July 2008, according to a statement from the Treasury Department. He later fled to nearby Gambia in August 2008, returning to Guinea-Bissau over a year later. He apparently feared for his life and sought refuge inside the United Nations Peacebuilding Support Office in Bissau, the country's capital.

The U.S. believes the former navy chief also was involved in organizing an April 2010 attempt to overthrow the Guinea-Bissau government.

Fernando Vaz, the spokesman for the government of Guinea-Bissau, said he hoped America would provide Na Tchuto a fair legal defense.

Guinea-Bissau has been plagued by coups. The last few, including one last year, are believed to have been fueled by an internal power struggle over which wing of the military would control the drug trade.

A booming cocaine trade has turned Guinea-Bissau into a narco-state. Key members of the military have been named as complicit in the trade, including several army and navy chiefs who are now on the United States' drug kingpin list. The infusion of illicit cash has emboldened an already bloated army. Drugs, observers say, played a role in the recent coup.

The arrest of Na Tchuto comes amid rumors of another looming coup in the capital.

Antonio Indjai, chief of staff of the country's armed forces, told reporters Thursday that reports that a coup was under way were false.

"They're only speculation by people of bad faith that serve to destabilize the country," Indjai said in the capital of Bissau, according to comments reported by the Agencia Noticiosa da Guine-Bissau news agency.

---

Yost reported from Washington. AP writers including Lassana Cassama in Bissau, Guinea-Bissau; Barry Hatton in Lisbon, Portugal; Rukmini Callimachi in Dakar, Senegal, and Alan Clendenning in Madrid contributed to this report.

Source: http://seattletimes.com/html/politics/2020717341_apusguineabissauarrest.html?syndication=rss

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Japan adopts stimulus plan to aid recovery

Japan adopts stimulus plan to aid recovery

Tokyo ? Japan is taking aggressive action to lift consumer prices, encourage borrowing and help pull the world?s third-largest economy out of a long slump.

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Source: http://www.detroitnews.com/article/20130405/BIZ/304050339/1001/rss21

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Roger Ebert, the Heart and Soul of the Movies, Has Died

BUCHAREST, April 5 (Reuters) - Highly-rated Romania defender Stefan Radu is retiring from international soccer at 26 to concentrate on his club career with Serie A side Lazio. Radu's agent Ioan Becali informed Romania coach Victor Piturca that the player was quitting the national side for personal reasons. "Mr. Becali already told you," left back Radu, who can also play as a central defender, told local media on Friday. "It's not a big loss, there are enough quality players in the Romanian team. ...

Source: http://news.yahoo.com/roger-ebert-heart-soul-movies-died-193948667.html

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North Dakota Sen. Heidi Heitkamp, Indiana Sen. Joe Donnelly now say they support gay marriage (Star Tribune)

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Your First Computer Love Deserves a Place in Your Heart and On Your Wall

Maybe the old computers you've been hoarding are broken. Maybe you just got rid of them before the nostalgia set in. Either way, these slick schematic prints of classic computers are a great way to give a shout-out to the gadgets you love without devoting any of your precious shelf-space to a dinosaur. More »


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/Vd4fZa2yK7I/your-first-computer-love-deserves-a-place-in-your-heart-and-on-your-wall

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